September 25, 2005 - May 21, 2006

The second season deals with Lynette going back at work; Gabrielle and her husband's baby quest; Susan and her on-going search for true love; Bree's family problems and alcoholism; Edie's continuing trouble-making; and the Applewhites, the new neighbors on Wisteria Lane. They seem friendly, but what are they hiding?

September 24, 2006 - May 20, 2007

Six months after the events of the second season finale, things are still juicy on Wisteria Lane. Gabrielle is divorcing her husband; Tom's one time lover and love child are stirring up things in Lynette's life; Susan is caught in yet another love-triangle; Edie is going after two of her friends' leftovers; and Bree is marrying a mysterious man with a secret.

September 30, 2007 - May 18, 2008

In the fourth season, Lynette deals with cancer and Tom's evil love child; Bree fakes her pregnancy to protect her daughter; Gabrielle and Carlos begin an affair; Susan's new marriage with Mike doesn't seem as perfect as she thought; Edie continues to force her relationship with Carlos; and new neighbor Katherine Mayfair and her family move in. What could Katherine be hiding?

September 28, 2008 - May 17, 2009

Five years after the events of the fourth season finale, Gabrielle finds life hards with two children and a blind husband; Lynette's children are still as trouble-making as before; Bree becomes a successful cookbook writer; Susan, who begins an affair with her painter, and Katherine, who's still living on the Lane, are caught in a nasty love-triangle with Mike; and Edie moves back with a new husband, who doesn't seem very nice.

September 27, 2009 - May 16, 2010

In the sixth season, Bree and Karl, Susan's ex-husband, begin an adulterous affair; Lynette struggles with her pregnancy; Gabrielle finds it hard to care for Carlos' niece as well as her two children; the Susan/Mike/Katherine love-triangle continues; and Angie Bolen and her husband and son are the new neighbors. What is Angie's secret? And what is she running away from?